Susceptibility to Rheumatic Fever

Susceptibility to Acute Rheumatic Fever

Acute rheumatic fever is a major cause of heart disease in large parts of the world, but it remains unknown why only a small fraction of those who are infected with rheumatogenic group A streptococci develop an abnormal immune response that leads to acute rheumatic fever. An understanding of the mechanisms underlying host susceptibility can provide important insights into pathogenesis that in t...

Pattern of hereditary susceptibility in rheumatic fever.

Age Susceptibility to Familial Infection in Rheumatic Fever.

One expression of our changing views with regard to rheumatic fever is the increasing importance being attached to juvenile forms of the disease. Older figures on the age incidence of this disease were based largely upon the incidence of both the primary, and recurrent attacks. Such figures minimized the importance of childhood as the period of greatest susceptibility. For instance in Rolly's m...

Immunologic Factors in Acute Rheumatic Fever Compared to Rheumatic Heart Disease

Background/Objective: To clarify the state of different immunologic factors in patients with acute rheumatic fever (ARF) and rheumatic heart disease (RHD) compared to healthy individuals.Patients and Methods: Patients with ARF (#21), patients with RHD six months after the onset of ARF (#19), and healthy children from the same age group with normal physical examination and no history of pharyngi...

Cutaneous Manifestations of Rheumatic Fever in Children

Sur 2601 admissions, chez 113 enfants at­teints de la maladie de Bouillaud, hospitalises en cinq ans dans deux services de pediatrie de Te­heran (C.H.U. de Pahlavi, C.H.U. de Logman­doleh Adham) 6 cas de manifestations cutanees  (trois cas de nodules, trois cas d'erytheme mar­ginatum) ont ete constates, trois d'entre eux souffrant d'une cardite severe et evolutive.  En Iran !'incidence des si...